William Irvine Fraser

William P . Hanage , Christophe Fraser and Brian G . Spratt *

Whatever else they should share, strains of bacteria assigned to the same species should have housekeeping genes that are similar in sequence. Single gene sequences (or rRNA gene sequences) have very few informative sites to resolve the strains of closely related species, and relationships among similar species may be confounded by interspecies recombination. A more promising approach (multiloc...

UC Irvine UC Irvine Previously

Background: To model and thoroughly understand animal transcription networks, it is essential to derive accurate spatial and temporal descriptions of developing gene expression patterns with cellular resolution. Results: Here we describe a suite of methods that provide the first quantitative three-dimensional description of gene expression and morphology at cellular resolution in whole embryos....

UC Irvine UC Irvine

UC Irvine UC Irvine

UC Irvine UC Irvine Previously